Leukocyte Depletion in Cardiac Surgery and Cardiology


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INTRODUCTION

Total anomalous pulmonary venous connection: an analysis of current management strategies in a single institution. Long-term outcome of surgically treated patients with corrected transposition of the great arteries. The independent role of cyclic flexure in the early in vitro development of an engineered heart valve tissue. Heart valve regeneration.

Adv Biochem Eng Biotechnol. Acute myeloid leukemia treatment in patients over 60 years of age. Comparison of symptomatic, palliative, and aggressive therapy. Risk factors for readmission after neonatal cardiac surgery. Application of tissue-engineering principles toward the development of a semilunar heart valve substitute. Intermediate outcomes of atrioventricular valvuloplasty in lateral tunnel Fontan patients. Long-term predictors of aortic root dilation and aortic regurgitation after arterial switch operation.

Tissue-engineered microvessels on three-dimensional biodegradable scaffolds using human endothelial progenitor cells. Design and hydrodynamic evaluation of a novel pulsatile bioreactor for biologically active heart valves. Aortico-left ventricular tunnel: year experience. Can a patient educational book change behavior and reduce pain in chronic low back pain patients? Modification to the Fontan procedure for the prophylaxis of intra-atrial reentrant tachycardia: short-term results of a prospective randomized blinded trial.

A structural constitutive model for the native pulmonary valve. The STS future planning conference for adult cardiac surgery. The influence of hemodilution on outcome after hypothermic cardiopulmonary bypass: results of a randomized trial in infants. Staged repair of tetralogy of Fallot and diminutive pulmonary arteries with a fenestrated ventricular septal defect patch. Atrial tachyarrhythmias and permanent pacing after pediatric heart transplantation.

J Heart Lung Transplant. Is a learning curve for arterial switch operation in small countries still acceptable? Model for cooperation in Europe. A novel bioreactor for the dynamic flexural stimulation of tissue engineered heart valve biomaterials. Dynamic rotational seeding and cell culture system for vascular tube formation. Thoracic Surgery Directors Association Award. Bone marrow as a cell source for tissue engineering heart valves. Time course of early induction of intracellular adhesion molecule-1 messenger RNA during reperfusion, following cardiopulmonary bypass with hypothermic circulatory arrest in lambs.

Effect of L-arginine or nitroglycerine during deep hypothermic circulatory arrest in neonatal lambs. Ethical and regulatory issues concerning engineered tissues for congenital heart repair. Improving results of the modified Fontan operation in patients with heterotaxy syndrome. Gastrointestinal complications after pediatric cardiac transplantation.

Advances in the mechanisms of cell delivery to cardiovascular scaffolds: comparison of two rotating cell culture systems. Arterial switch operation with a single coronary artery. Valved homograft replacement of aneurysmal pulmonary arteries for severely symptomatic absent pulmonary valve syndrome.

The contribution of aerobic fitness and back strength to lift capacity. Spine Phila Pa Evolution of cell phenotype and extracellular matrix in tissue-engineered heart valves during in-vitro maturation and in-vivo remodeling. Phys Rev Lett. Experience of a single center]. Outcome after reconstruction of discontinuous pulmonary arteries. Measurement of the strong coupling constant from inclusive jet production at the Tevatron pp collider.

Apical ventricular septal defects: follow-up concerning anatomic and surgical considerations. Myocardial immediate early gene activation after cardiopulmonary bypass with cardiac ischemia-reperfusion. The stiffness of bone marrow cell-knit composites is increased during mechanical load. Treatment of acute hepatitis C with interferon alfa-2b. Perioperative risk factors for development of protein-losing enteropathy following a Fontan procedure. Double diffraction dissociation at the Fermilab Tevatron collider. Functional small-diameter neovessels created using endothelial progenitor cells expanded ex vivo.

Nat Med. Measurement of the top quark p T distribution. In search of the ideal valve replacement device. Long-term results after early primary repair of tetralogy of Fallot. Paucity of sinus node dysfunction following repair of sinus venosus defects in children. Task force 4: organization of delivery systems for adults with congenital heart disease. Surgery for coarctation of the aorta in infants weighing less than 2 kg. Dynamics of extracellular matrix production and turnover in tissue engineered cardiovascular structures.

J Cell Biochem. Fetal tissue engineering: diaphragmatic replacement. Long-term results of the lateral tunnel Fontan operation. Surgical outcome of double-outlet right ventricle with subpulmonary VSD. Outcome in infants with pulmonary atresia, intact ventricular septum, and right ventricle-dependent coronary circulation. Patch augmentation of the pulmonary artery with bioabsorbable polymers and autologous cell seeding.

Functional living trileaflet heart valves grown in vitro. Early in vivo experience with tissue-engineered trileaflet heart valves. Surgical management of mitral regurgitation after repair of endocardial cushion defects: early and midterm results. Clinical outcome of fenestrated Fontan patients after closure: the first 10 years. Surgery for bilateral outflow tract obstruction in elastin arteriopathy. Sialyl LewisX oligosaccharide preserves myocardial and endothelial function during cardioplegic ischemia. Treatment of hospital-acquired penumonia.

Semin Respir Infect. Cognitive development after the Fontan operation. Sialyl lewis oligosaccharide preserves cardiopulmonary and endothelial function after hypothermic circulatory arrest in lambs. Twenty-five-year experience with rastelli repair for transposition of the great arteries. Cardiac performance after deep hypothermic circulatory arrest in chronically cyanotic neonatal lambs. Tissue engineering of heart valves: in vitro experiences. Minimal access approach for the repair of atrial septal defect: the initial patients. Surgical management of complex and tunnel-like subaortic stenosis.

First FDA approval under humanitarian device exemption of a septal occluder for fenestrated fontan and muscular ventricular septal defects. Catheter Cardiovasc Interv.


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First Food and Drug Administration approval under humanitarian device exemption of a septal occluder for fenestrated fontan and muscular ventricular septal defects. Tissue-engineered valved conduits in the pulmonary circulation. Fabrication of a trileaflet heart valve scaffold from a polyhydroxyalkanoate biopolyester for use in tissue engineering. Repair of the truncal valve and associated interrupted arch in neonates with truncus arteriosus.

Matrices for tissue engineering-scaffold structure for a bioartificial liver support system. J Control Release. New pulsatile bioreactor for in vitro formation of tissue engineered heart valves. Results of Norwood stage I operation: comparison of hypoplastic left heart syndrome with other malformations.

Evaluation of biodegradable, three-dimensional matrices for tissue engineering of heart valves. Management of pulmonary arteriovenous malformations after surgery for complex congenital heart disease. Preparation and in vivo testing of porous alumina ceramics for cell carrier applications. Improved results with selective management in pulmonary atresia with intact ventricular septum. Tissue engineering of autologous aorta using a new biodegradable polymer.

Repair of tetralogy of Fallot in neonates and young infants. Forty-one years of surgical experience with congenital supravalvular aortic stenosis. Myocardial self-preservative effect of heat shock protein 70 on an immature lamb heart. Tissue engineering of a trileaflet heart valve-early in vitro experiences with a combined polymer. Embryo implantation in in vitro fertilization and intracytoplasmic sperm injection: impact of cleavage status, morphology grade, and number of embryos transferred.

Fertil Steril. Perifollicular blood flow Doppler indices, but not follicular pO2, pCO2, or pH, predict oocyte developmental competence in in vitro fertilization. Aneuploidy frequencies in semen fractions from ten oligoasthenoteratozoospermic patients donating sperm for intracytoplasmic sperm injection.

Pediatric lung transplantation and "lessons from Green Surgery. Artif Organs. Valved homograft conduit repair of the right heart in early infancy.

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Effects of cyanosis and hypothermic circulatory arrest on lung function in neonatal lambs. Evolution of risk factors influencing early mortality of the arterial switch operation.

Mechanical circulatory support in children with cardiac disease. Left ventricular assist device improves survival in children with left ventricular dysfunction after repair of anomalous origin of the left coronary artery from the pulmonary artery. Valves in development for autogenous tissue valve replacement. Effects of a monoclonal antibody to P-selectin on recovery of neonatal lamb hearts after cold cardioplegic ischemia. High-volume continuous hemofiltration during cardiopulmonary bypass attenuates pulmonary dysfunction in neonatal lambs after deep hypothermic circulatory arrest.

Acute pulmonary embolism in a neonate: precipitation during cardiac catheterization and successful treatment. Validation of relative value scale for congenital heart operations. Duration of complete atrioventricular block after congenital heart disease surgery. Use of rapid-deployment extracorporeal membrane oxygenation for the resuscitation of pediatric patients with heart disease after cardiac arrest. Utility of intraoperative transesophageal echocardiography in the assessment of residual cardiac defects.

Effects of adenosine infusion with or without leukocyte depletion on recovery after hypothermic ischemia in neonatal lamb hearts. Use of an ultrasonic scalpel as an alternative to electrocautery in patients with pacemakers. Long-term performance of bipolar epicardial atrial pacing using an active fixation bipolar endocardial lead. Pacing Clin Electrophysiol. Creation of viable pulmonary artery autografts through tissue engineering. The outcome of clinical pregnancies following intracytoplasmic sperm injection is not affected by semen quality.

Late outcome after the Fontan procedure. Impact of fertilization history and semen parameters on ICSI outcome. J Assist Reprod Genet. Perioperative effects of alpha-stat versus pH-stat strategies for deep hypothermic cardiopulmonary bypass in infants. Tissue-engineered heart valve leaflets: does cell origin affect outcome? Soluble adhesion molecules in infants and children undergoing cardiopulmonary bypass.

Relationship of blood flow effects of adenosine during reperfusion to recovery of ventricular function after hypothermic ischemia in neonatal lambs. Tissue engineering of cardiovascular structures. Curr Opin Cardiol. Fontan operation in five hundred consecutive patients: factors influencing early and late outcome. Functional outcome after the Fontan operation: factors influencing late morbidity. Induction of aquaporin-1 mRNA following cardiopulmonary bypass and reperfusion. Mol Med. High-rate atrial pacing as an innovative bridging therapy in a neonate with congenital long QT syndrome.

J Cardiovasc Electrophysiol. The efficacy of tranexamic acid versus placebo in decreasing blood loss in pediatric patients undergoing repeat cardiac surgery. Evaluation of a staged treatment protocol for rapid automatic junctional tachycardia after operation for congenital heart disease. The in vitro construction of a tissue engineered bioprosthetic heart valve. An institutional experience with second- and third-stage palliative procedures for hypoplastic left heart syndrome: the impact of the bidirectional cavopulmonary shunt.

Factors that influence the development of atrial flutter after the Fontan operation. Outcome of patients with ectopia cordis and significant intracardiac defects. Blockade of selectin-mediated leukocyte adhesion improves postischemic function in lamb hearts. Tissue-engineered heart valves. Autologous valve leaflet replacement study in a lamb model. Hypoxia enhances stimulus-dependent induction of E-selectin on aortic endothelial cells.

Tissue engineering lamb heart valve leaflets. Biotechnol Bioeng. Tetralogy of Fallot with diminutive pulmonary arteries: preoperative pulmonary valve dilation and transcatheter rehabilitation of pulmonary arteries. Conversion of modified Fontan procedure to lateral atrial tunnel cavopulmonary anastomosis. Long-term outcome in patients with pacemakers following the Fontan operation. Staged operation to Fontan increases the incidence of sinoatrial node dysfunction. Tissue engineering scaffolds using superstructures.

Hypoxic stress alone does not modulate endothelial surface expression of bovine E-selectin and intercellular adhesion molecule-1 ICAM Swiss Surg Suppl. Effects of endothelin-1 and L-arginine after cold ischemia in lamb hearts. Myocardial mechanics before and after ablation of chronic tachycardia. Tissue engineering heart valves: valve leaflet replacement study in a lamb model.

Age differences in effects of hypothermic ischemia on endothelial and ventricular function. Anti-CD11b monoclonal antibody improves myocardial function after six hours of hypothermic storage. Effects of endothelin-1 and endothelin-A receptor antagonist on recovery after hypothermic cardioplegic ischemia in neonatal lamb hearts. Induction of interleukin-8 messenger RNA in heart and skeletal muscle during pediatric cardiopulmonary bypass.

Sternotomy approach for the modified Blalock-Taussig shunt. Effect of L-arginine cardioplegia on recovery of neonatal lamb hearts after 2 hours of cold ischemia. Effects of elevated coronary sinus pressure on coronary blood flow and left ventricular function. Implications after the Fontan operation. Ten-year institutional experience with palliative surgery for hypoplastic left heart syndrome. Risk factors related to stage I mortality. Postoperative course and hemodynamic profile after the arterial switch operation in neonates and infants.

A comparison of low-flow cardiopulmonary bypass and circulatory arrest. P-selectin expression in myocardium of children undergoing cardiopulmonary bypass.

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Hepatic venous blood and the development of pulmonary arteriovenous malformations in congenital heart disease. Uses of homograft conduits for right ventricle to pulmonary artery connections in the neonatal period. Additive effects of L-arginine infusion and leukocyte depletion on recovery after hypothermic ischemia in neonatal lamb hearts. Partial or total direct pulmonary venous drainage to right atrium due to malposition of septum primum. Anatomic and echocardiographic findings and surgical treatment: a study based on 36 cases.

Cardiac catheterization and test occlusion of the interatrial communication after the fenestrated Fontan operation. Cerebrovascular accidents following the Fontan operation. Pediatr Neurol. Arrhythmias and intracardiac conduction after the arterial switch operation. Factors influencing early and late outcome of the arterial switch operation for transposition of the great arteries. Anastomotic pseudoaneurysm of the ventricle after homograft placement in children.

Effects of L-arginine and L-nitro-arginine methyl ester on recovery of neonatal lamb hearts after cold ischemia. Evidence for an important role of endothelial production of nitric oxide. Surgical alternatives to the Fontan procedure incorporating a hypoplastic right ventricle. Unique features and prognosis of primum ASD presenting in the first year of life. Effects of hypercarbic acidotic reperfusion on recovery of myocardial function after cardioplegic ischemia in neonatal lambs. Extragenital infection due to Mobiluncus mulieris.

Case report and review. Diagn Microbiol Infect Dis. Maturational and hemodynamic factors predictive of increased cyanosis after bidirectional cavopulmonary anastomosis. Coronary echocardiography in patients with d-loop transposition of the great arteries. Size disparity in pediatric lung transplantation. Sinus venosus defects: unroofing of the right pulmonary veins--anatomic and echocardiographic findings and surgical treatment. Am Heart J.

Leukocyte Depletion in Cardiac Surgery and Cardiology (2001, Hardcover)

Induction of intercellular adhesion molecule-1 and E-selectin mRNA in heart and skeletal muscle of pediatric patients undergoing cardiopulmonary bypass. Interactions between preischemic hypothermia and cardioplegic solutions in the neonatal lamb heart. Result of biventricular repair for double-outlet right ventricle. Total anomalous pulmonary venous drainage in newborns with visceral heterotaxy.

Initial management of the single ventricle patient. Antiparasitic effects of nitric oxide in an in vitro murine model of Chlamydia trachomatis infection and an in vivo murine model of Leishmania major infection. Immunol Ser. Effects of adenosine infusion during reperfusion after cold cardioplegic ischemia in neonatal lambs. Right ventricular decompression and left ventricular function in pulmonary atresia with intact ventricular septum.

The influence of less extensive coronary anomalies. Early bidirectional cavopulmonary shunt in young infants. Postoperative course and early results. Nitroglycerin improves functional recovery of neonatal lamb hearts after 2 hours of cold ischemia. Intraoperative device closure of ventricular septal defects. Influence of right heart size on outcome in pulmonary atresia with intact ventricular septum. A comparison of the perioperative neurologic effects of hypothermic circulatory arrest versus low-flow cardiopulmonary bypass in infant heart surgery.

Tetralogy of Fallot with pulmonary atresia. Rehabilitation of diminutive pulmonary arteries. Invited letter concerning: normocalcemic blood or crystalloid cardioplegia provides superior neonatal myocardial protection over low-calcium cardioplegia J Thorac Cardiovasc Surg ; J Thorac Cardiovasc Surg. Surgical repair of complete atrioventricular canal defects in infancy. Twenty-year trends. Diagnosis of intramural coronary artery in transposition of the great arteries using two-dimensional echocardiography.

Growth of the aortic anastomosis, annulus, and root after the arterial switch procedure performed in infancy. Individual pulmonary vein size and survival in infants with totally anomalous pulmonary venous connection. Prevalence and risk factors for aortopulmonary collateral vessels after Fontan and bidirectional Glenn procedures. Conal anatomy in patients with d-loop transposition of the great arteries and ventricular septal defect: an echocardiographic and pathologic study.

Repair of truncus arteriosus in the neonate. Fate of small homograft conduits after early repair of truncus arteriosus. Recent evidence on drug therapy of mild to moderate hypertension and decreased risk of coronary heart disease. Arch Intern Med. An analysis of ischemic stroke in an urban southern California population. Anti-CD18 attenuates myocardial stunning in the isolated neonatal lamb heart. Effect of calcium and preischemic hypothermia on recovery of myocardial function after cardioplegic ischemia in neonatal lambs.

Gamma interferon-induced nitric oxide production reduces Chlamydia trachomatis infectivity in McCoy cells.

DCRV Congenital heart Surgery - Pediatric Heart Surgery

Infect Immun. Natural history and patterns of recovery of contractile function in single left ventricle after Fontan operation. Effect of baffle fenestration on outcome of the modified Fontan operation. Diagnosis and management of right ventricle-dependent coronary circulation in pulmonary atresia with intact ventricular septum. Effect of antibody to leukocyte adhesion molecule CD18 on recovery of neonatal lamb hearts after 2 hours of cold ischemia. Coronary endothelial injury by cold crystalloid cardioplegic solution in neonatal lambs.

Temperature monitoring during CPB in infants: does it predict efficient brain cooling? Unusual complication of temporary pacing wires in children. Transcatheter ablation of ectopic atrial tachycardia in young patients using radiofrequency current. Evidence for the role of neutrophils in reperfusion injury after cold cardioplegic ischemia in neonatal lambs. Morphologic and surgical determinants of outcome events after repair of tetralogy of Fallot and pulmonary stenosis. A two-institution study. Factors associated with marked reduction in mortality for Fontan operations in patients with single ventricle.

Fontan procedure for hypoplastic left heart syndrome. Bulboventricular foramen size in infants with double-inlet left ventricle or tricuspid atresia with transposed great arteries: influence on initial palliative operation and rate of growth. Two-dimensional echocardiography in the pre- and postoperative management of totally anomalous pulmonary venous connection.

Fluconazole failure in the treatment of invasive mycoses. J Infect Dis. Function of the anatomic pulmonary valve in the systemic circulation. Differences in cancer-risk-related behaviors in Latino and Anglo adults. Prev Med. Corrected transposition in situs inversus. Biventricular repair of associated cardiac anomalies. Straddling mitral valve with hypoplastic right ventricle, crisscross atrioventricular relations, double outlet right ventricle and dextrocardia: morphologic, diagnostic and surgical considerations.

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Preoperative transcatheter closure of congenital muscular ventricular septal defects. Influence of initial reperfusion pressure after hypothermic cardioplegic ischemia on endothelial modulation of coronary tone in neonatal lambs. Impaired coronary vasodilator response to acetylcholine. Cognitive development of children following early repair of transposition of the great arteries using deep hypothermic circulatory arrest.

Myocardial preservation in neonatal lambs. Comparison of hypothermia with crystalloid and blood cardioplegia. Inhibition of contraction of isolated lymphatic ducts by atrial natriuretic peptide. Am J Physiol. Pediatric cardiac surgery. Invited letter concerning: coarctation. Development, growth, and cardiac surgery. Am J Dis Child. Neonatal repair of tetralogy of Fallot with and without pulmonary atresia. Cardiac transplantation for neonates with hypoplastic left heart syndrome.

Coronary artery pattern and outcome of arterial switch operation for transposition of the great arteries. Mitral valve replacement in the first year of life. Results of the arterial switch operation in patients with transposition of the great arteries and abnormalities of the mitral valve or left ventricular outflow tract.

Bidirectional cavopulmonary anastomosis as interim palliation for high-risk Fontan candidates. Early results. Invited letter concerning: rapid cooling contracture of the myocardium. The "laid-back" aortogram: an improved angiographic view for demonstration of coronary arteries in transposition of the great arteries. Fungal elicitor triggers rapid, transient, and specific protein phosphorylation in parsley cell suspension cultures. J Biol Chem. Orthotopic heart transplantation for complex congenital heart disease.

Role of lung biopsy in patients undergoing a modified Fontan procedure. A new complication of left atrial catheters. J Cardiothorac Anesth. Results of the arterial switch operation for transposition of the great arteries with ventricular septal defect. Surgical considerations and midterm follow-up data. The neonate with critical congenital heart disease: repair--a surgical challenge. Rapid, two-stage arterial switch for transposition of the great arteries and intact ventricular septum beyond the neonatal period. Rapid two-stage arterial switch operation for TGA. Nihon Kyobu Geka Gakkai Zasshi.

Neonatal repair of Fallot's tetralogy with and without pulmonary atresia. Transposition of the great arteries: the arterial switch operation. Cardiol Clin. Aortic atresia with normal left ventricle. Single-stage repair in the neonate. Brain tissue pH, oxygen tension, and carbon dioxide tension in profoundly hypothermic cardiopulmonary bypass. Echocardiographic and anatomic findings in atrioventricular discordance with ventriculoarterial concordance. The results of a surgical program for interrupted aortic arch. Invited letter concerning: total cavopulmonary connection.

Myocardial protection in cyanotic neonatal lambs. Midterm results after the arterial switch operation for transposition of the great arteries with intact ventricular septum: clinical, hemodynamic, echocardiographic, and electrophysiologic data. This study suggests that sex-mismatched blood transfusions may create a high enough risk to necessitate a change in transfusion protocols.

Further, many countries already have universal strategies to use leukocyte-depleted PRBC, and perhaps this study should call for the United States to pursue the same policy. Transfusing sex-mismatched red blood cells RBCs was associated with an increased risk of death in people undergoing heart bypass surgery or aortic valve replacement, based on results of a retrospective single-center study of almost 10, transfusions in cardiac surgery patients. Each unit of sex-mismatched red blood cells RBCs transfused was associated with an increased risk of death hazard ratio, 1.

In addition, transfusing units of non—leukocyte depleted RBCs was associated with a significant increase in the risk of death during the first year after surgery HR, 1. Transfusion of units of leukocyte-depleted RBCs and the age of blood products was not associated with increased mortality J Thorac Cardiovasc Surg. The study involved 9, patients at Lund University from to 7, had coronary artery bypass grafting CABG ; 1, had aortic valve replacement AVR ; and concomitantly had both procedures.

References

Compared with the group that did not receive PRBC transfusions, the transfused group had significantly higher rates of heart attack after surgery 1. Based on an analysis that factored in 24 different variables, transfusion of units of non—leukocyte depleted PRBCs was associated with a HR of 1. However, transfusion of units of leukocyte-depleted RBCs was associated with decreased survival, as was transfusion of sex-mismatched PRBCs, associated with a HR of 1. Bjursten and colleagues wrote. Additionally, the increased death rate in the PRBC transfusion group may have been related to age and comorbidities such as diabetes, chronic obstructive pulmonary disease, and cardiac insufficiency.

Bjursten and coauthors said.

Leukocyte Depletion in Cardiac Surgery and Cardiology Leukocyte Depletion in Cardiac Surgery and Cardiology
Leukocyte Depletion in Cardiac Surgery and Cardiology Leukocyte Depletion in Cardiac Surgery and Cardiology
Leukocyte Depletion in Cardiac Surgery and Cardiology Leukocyte Depletion in Cardiac Surgery and Cardiology
Leukocyte Depletion in Cardiac Surgery and Cardiology Leukocyte Depletion in Cardiac Surgery and Cardiology
Leukocyte Depletion in Cardiac Surgery and Cardiology Leukocyte Depletion in Cardiac Surgery and Cardiology
Leukocyte Depletion in Cardiac Surgery and Cardiology Leukocyte Depletion in Cardiac Surgery and Cardiology
Leukocyte Depletion in Cardiac Surgery and Cardiology Leukocyte Depletion in Cardiac Surgery and Cardiology
Leukocyte Depletion in Cardiac Surgery and Cardiology Leukocyte Depletion in Cardiac Surgery and Cardiology
Leukocyte Depletion in Cardiac Surgery and Cardiology Leukocyte Depletion in Cardiac Surgery and Cardiology

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